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Home Antibody All anti-WFS1 antibodies

Anti-WFS1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301684
  • Rabbit Polyclonal Antibody against WFS1 - Endoplasmic Reticulum Marker
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416929) , 20ug Explanation
100ul 325 In Stock
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WB(2)
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Also for WFS1 (NM_006005)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA 110 amino acid region of the N-terminal region of the human protein
Clone Name IsotypeIgG
Species Reactivityhuman, rat, mouse ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000
Buffer
Purification Whole antisera

Reference Data

Target NameHomo sapiens Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 1
Alternative NameCTRCT41; WFRS; WFS; WFSL
Database LinkNP_005996
Entrez Gene 7466 Human
Entrez Gene 22393 Mouse
Entrez Gene 83725 Rat
FunctionWFS1 is a novel component of Wolfram syndrome, a rare form of juvenile diabetes. WFS1 plays an important role in maintaining homeostasis of the endoplasmic reticulum (ER) in the pancreas. It is normally up-regulated during insulin secretion, whereas inactivation of the protein can cause ER stress. Chronic ER stress is a major involvement in Wolfram syndrome.
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

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Western Blot: WFS1 Antibody TA301684 - Analysis of WFS1 in insulinoma cells.
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Detection of WFS1 in insulinoma cells

 

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