Home Antibody All anti-CYP46A1 antibodies
Also for CYP46A1 (NM_006668)
|A synthetic peptide corresponding to residues between 200-250 of human Cyp46.|
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||WB: 1: 1000
|Homo sapiens cytochrome P450, family 46, subfamily A, polypeptide 1 (CYP46A1)|
Entrez Gene 10858 Human
|The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum proein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol.|
|P450Druggable Genome Primary bile acid biosynthesis|
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Western analysis of Cyp-46 in HEK293 cells overexpressing CYP46A1 or transfected with an empty vector
Detection of Cyp46 in human cortex
Immunocytochemistry/Immunofluorescence: CYP46A1 antibody was tested in SH-SY5Y cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).