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Anti-TERT Antibody 2C4
Also for TERT (NM_198253)
|Full-length recombinant hTERT from insect cells.|
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF, FC
|0.05% sodium azide|
|Homo sapiens telomerase reverse transcriptase (TERT), transcript variant 1|
|CMM9; DKCA2; DKCB4; EST2; hEST2; hTRT; PFBMFT1; TCS1; TP2; TRT|
|Telomeres are nucleoprotein structures at the ends of eukaryotic chromosomes. They regulate several crucial cellular functions and participate in the control of complex phenotypes, such as aging and cancer. Cell immortalization is strongly associated with the stabilization of telomere length. Therefore, it is suggested that cancer cells achieve immortalization in part through illegitimate activation of telomerase expression. hTERT is the rate-limiting catalytic subunit of telomerase. Telomerase is an enzyme uniquely associated with immortal cell lines and is useful for identifying undifferentiated PSCs. |
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Western Blot analysis of human TERT 1:500 dilution on MJ90 cells
Normal pancreas showing moderate staining of exocrine cells and a subset of islets of Langerhans
Immunocytochemistry/Immunofluorescence: Telomerase reverse transcriptase Antibody (2C4) - Detection of Tert (Green) in HepG2 cells. Nuclei (Blue) are counterstained with Hoechst 33258.
Flow Cytometry: Telomerase reverse transcriptase Antibody (2C4) - Staining of NTERA-2 cells at a 1:200 dilution detected using Dylight-488 conjugated goat anti-mouse IgM secondary antibody.