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Anti-CREB1 PHOSPHO Antibody
Also for CREB1 (NM_004379)
|A phospho-peptide spanning the Ser-121 phosphorylation site of human CREB.|
||WB: 1:500, IP:5 ug/ml
|Tris 50% glycerol and 0.05% sodium azide|
|Homo sapiens cAMP responsive element binding protein 1 (CREB1), transcript variant A|
|Cyclic AMP Response Element Binding protein (CREB) is a basic / leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth and neurotrophic factors. CREB is also regulated by DNA-damaging stimuli and is directly phosphorylated on Ser-121 by the ataxia-telangiectasia-mutated protein kinase, ATM in response to ionizing radiation.|
EGFR1 Signaling Pathway
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Detection of phospho-CREB in human HEK 293T cells. Top panel: probed with phosph-CREB. Bottom panel: probed with CREB antibody. Lanes 2 and 4 treated with lambda phosphatase, lanes 3 and 4 treated with 0.2mM H202.