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Anti-APOA5 Antibody 1G5G9


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA301561 Mouse Monoclonal Antibody against Apo A5 (1G5G9) 100ul $325 3-7 Days
LC403279 APOA5 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenNi-NTA purified full-length recombinant human APOA5 expressed in E. Coli strain BL21 (DE3).
Clone Name1G5G9 IsotypeIgG1 kappa
Species Reactivityhuman Concentration3.6 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000

Reference Data

Target NameHomo sapiens apolipoprotein A-V (APOA5), transcript variant 1
Alternative NameAPOAV; RAP3
Database LinkNP_443200
Entrez Gene 116519 Human
FunctionApolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four-fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-4 (PPAR-alpha) agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentrations than other apolipoproteins.
Related PathwaySecreted ProteinDruggable Genome PPAR signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis using anti- human APOA5 monoclonal antibody against human serum total protein (lane 2). Lane 1 is a MW standard

WB Image
Western Blot: Apolipoprotein A5 Antibody (1G5G9) - Detection of Apo A5 in HepG2 cell lysate.


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