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Home Antibody All anti-IFT57 antibodies

Anti-IFT57 Antibody 1E1

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301535
  • Mouse Monoclonal Antibody against HIP1 Receptor (1E1)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402637) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for IFT57 (NM_018010)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenHuman HIP1r-TALIN Homology Region (57 kDa).
Clone Name1E1 IsotypeIgG1 kappa
Species Reactivityhuman, rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1: 1000
Buffer

Reference Data

Target NameHomo sapiens intraflagellar transport 57 homolog (Chlamydomonas) (IFT57)
Alternative NameESRRBL1; HIPPI; MHS4R2
Database LinkNP_060480
FunctionHuntingtin disease, a neurodegenerate disease, is caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin disease. As well as playing a role in Huntingtin disease, it is likely to be involved in the recruitment of clathrin coats to lipid membranes and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.
Related Pathway

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WB Image
Western Blot analysis of HIP1 protein in HeLa cell and rat brain lysates,

 

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