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Home All anti-DNM1L antibodies

Anti-DNM1L Antibody

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA301511
  • Rabbit Polyclonal Antibody against DRP1
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402138) , 20ug
100ul $325 In Stock
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
30ul
$100
$50*
In Stock
Add to Shopping Cart
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(2)
IHC(1)
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Also for DNM1L (NM_012062)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide made to an internal region within residues 500-600 of the human protein. [Swiss-Prot# O00429]
Clone Name Isotype
Species Reactivityhuman, primate, rat, mouse, hamster Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1: 1000
BufferTris-glycine, 150mM NaCl and 0.5% sodium azide
Purification Immunogen affinity purified (Protein A or G Sepharose)

Reference Data

Target NameHomo sapiens dynamin 1-like (DNM1L), transcript variant 1
Alternative NameDLP1; DRP1; DVLP; DYMPLE; DYNIV-11; EMPF; HDYNIV; VPS1
Database LinkNP_036192
FunctionA human dynamin-related protein, DRP1 contributes to mitochondrial division in mammalian cells. It plays this important role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, thus providing a genetic tool to assess the role of mitochondria at synapses.
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control or pCMV6-ENTRY DNM1L (RC221708) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DNM1L.
WB Image
Lane 1: DRP1 knockout, Lane 2: DRP1 wildtype MEFs at 1:500x dilution
IHC Image
Staining of renal tubular epithelium and visceral epithelial cells of the glomerulus at 2.5ug/ml. Human kidney cortex, 40X magnification

 

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