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Also for YAP1 (NM_006106)
|Recombinant YAP protein expressed in bacteria.|
||Lot dependent; please refer to CoA along with shipment
||WB: 1: 1000
|PBS, 15% glycerol and 0.02% sodium azide|
|Homo sapiens Yes-associated protein 1 (YAP1), transcript variant 2|
|COB1; YAP; YAP2; YAP65; YKI|
|YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. As one of several genes of 1q22 amplicon, YAP was recently implicated in liver and breast cancer. Overexpression of YAP gene in MCF10A mammary cell line induces oncogenic transformation.|
TGF Beta Signaling Pathway
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Detection of YAP protein in transfected HEK 293 cell lysate.
Immunocytochemistry/Immunofluorescence: The YAP antibody was tested in Hela cells at a 1:500 dilution against Dylight 488 (Green). Alpha tubulin and nuclei were counterstained against Dylight 550 (red) and DAPI (blue), respectively.