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Home Antibody All anti-SCARB1 antibodies

Anti-SCARB1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301489
  • Rabbit Polyclonal Antibody against SR-BI
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401684) , 20ug
100ul 325 In Stock
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WB(2)
IHC(2)
IF(1)
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Also for SCARB1 (NM_005505)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA C-terminal peptide containing residues from mouse Scavenger Receptor-BI (within residues 450-509).
Clone Name Isotypen/a
Species Reactivityhuman, mouse, rat, mink, hamster ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1: 1000-1:5000
BufferTris-citrate/phosphate [pH 7-8] buffer. and 0.1% Sodium Azide
Purification Affinity purified

Reference Data

Target NameHomo sapiens scavenger receptor class B, member 1 (SCARB1), transcript variant 1
Alternative NameCD36L1; CLA-1; CLA1; HDLQTL6; SR-BI; SRB1
Database LinkNP_005496
FunctionHigh density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
Related Pathway

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WB Image
Detection of SR-BI in 25 ug of mouse liver lysate, using anti-SRBI at a 1:1,000 dilution, shows distinct band at 82 kDa.
WB Image
Western Blot: SR-BI Antibody [NB400-104] - Detection of SR-BI in rat H4IIE total cell lysates and plasma membrane proteins.
IHC Image
Staining of adrenal, cortex
IHC Image
Immunohistochemistry: Immunolocalization of SR-BI in adult mink testis using SR-BI Antibody. SR-BI labeling is visible at the surface and along the outline of the large vacuole.
IF Image
Immunocytochemistry/Immunofluorescence: SRB1 antibody was tested at 1:50 in HeLa cells with FITC (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red).

 

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