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Home Antibody All anti-ATG5 antibodies

Anti-ATG5 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA301481 Rabbit Polyclonal Antibody against ATG5 100ul $325 2 Weeks
LC401532 ATG5 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide made to an N-terminal region (within residues 1-50) of the human ATG5 protein. [Swiss-Prot# Q9H1Y0]
Clone Name IsotypeIgG
Species Reactivityhuman, mouse, rat, cow, porcine, primate, Xenopus, Zebrafish Concentration1.16mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:500
BufferPBS plus 30% glycerol and 0.1% sodium azide
Purification peptide affinity purified

Reference Data

Target Nameautophagy related 5
Alternative NameAPG5|APG5-LIKE|APG5L|ASP|hAPG5
Database LinkNP_004840
Entrez Gene 9474 Human
Entrez Gene 11793 Mouse
Entrez Gene 365601 Rat
FunctionAutophagy is an important mechanism for nonselective intracellular breakdown whereby cytosol and organelles are encapsulated in vesicles, which are then engulfed and digested by lytic vacuoles/lysosomes. ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form autophagosomes. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Conjugation to ATG12 is essential for autophagy, but is not required for association with isolation membrane. ATG5 also plays an important role in the apoptotic process. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
Related PathwayDruggable Genome Regulation of autophagyRIG-I-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Detection of ATG5 in mouse wildtype ES cell lysate (Lane 1). Lane 2 is a mouse ATG5 KO ES cell lysate (negative control).

IHC Image
Staining of hepatocytes at 2.5ug/ml. Human liver hepatocytes 40X magnification.

IHC Image
Immunohistochemistry: ATG5 Antibody - Analysis of ATG5 in mouse intestine using DAB with hematoxylin counterstain.

IF Image
Immunofluorescent staining of SY5Y cells at 1:250. Incubated overnight at 4 degrees.


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