OriGene Logo
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-BAP1 antibodies

Anti-BAP1 Antibody 1G8

div

Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA301480 Mouse Monoclonal Antibody against BAP1 (1G8) 100ul $325 3-7 Days
LC401476 BAP1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
Add to Shopping Cart
spacer
WB(1)

OriGene Data

ImmunogenFull-length human BAP1 protein expressed and purified from E.coli. [Uniprot# Q92560]
Clone Name1G8 IsotypeIgG1 kappa
Species Reactivityhuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 2 ug/ml
BufferTris-glycine, 150mM NaCl and 0.05% sodium azide
Purification protein G purified

Reference Data

Target NameBRCA1 associated protein 1
Alternative NameHUCEP-13|UCHL2|hucep-6
Database LinkNP_004647
Entrez Gene 8314 Human
FunctionMutations within the BRCA1 gene, localized to chromosome 17q, are believed to account for approximately 45% of families with increased incidence of both early-onset breast cancer and ovarian cancer. The BRCA1 gene is expressed in numerous tissues, including breast and ovary, and encodes a predicted protein of 1863 amino acids. This protein contains a RING domain near the N-terminus and appears to encode a tumor suppressor. BARD1 (BRCA1-associated RING domain protein 1) and BAP1 (BRCA1-associated protein 1) have both been shown to bind to the N-terminus of BRCA1 and are potential mediators of tumor suppression. BARD1 contains an N-terminal RING domain and three tandem ankyrin repeats. The C-terminus of BARD1 contains a region with sequence homology to BRCA1, termed the BRCT domain. BAP1 is a ubiquitin hydrolase and has been shown to enhance BRCA1-mediated cell growth suppression.
Related PathwayProteaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
Detection of BAP1 in HeLa WCE (2ug/ml)
grey_line

 

spacer
Inc 5000 Healthcare Company

Notice to Non-US Customers

ExclaimationWeb price and delivery time are for direct sales only.

Non-US customers are encouraged to contact our dedicated distributor network for quotes and streamlined ordering/delivery support.

Acknowledge