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Home Antibody All anti-CAV1 antibodies

Anti-CAV1 Antibody 7C8

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301445
  • Mouse Monoclonal Antibody against Caveolin 1 (7C8)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400664) , 20ug
100ul 325 Next Day
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WB(1)
IF(1)

OriGene Data

ImmunogenGlut 4 vesicles.
Clone Name7C8 IsotypeIgG2b
Species Reactivityhuman, rat, mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IF Suggested DilutionsWB: 1: 1000-1:4000
BufferTris-glycine and 150mM NaCl containing 0.05% sodium azide. and Sodium Azide
Purification protein A purified

Reference Data

Target NameHomo sapiens caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant 1
Alternative NameBSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21
Database LinkNP_001744
FunctionCaveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo . Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.
Related Pathway
EGFR1 Signaling Pathway
Focal Adhesion
Hemostasis
TGF Beta Signaling Pathway

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WB Image
Detection of caveolin in 3T3 cell lysates (50 ug). Lanes 1 and 2: 1:4,000. Lanes 3 and 4: 1:1,000. ECL: 5 minute exposure.
IF Image
IF image at 1:200 dilution (ON incubation) on EaHy926 endothelial cell line showing a clear localization in lipid raft/membrane

 

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