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EPAS1 (Gene ID 2034) Antibody

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Catalog No. Description Amount Price Shipping *
TA301435
  • Mouse Monoclonal Antibody against HIF-2 alpha (ep190b)
100 ul $325 3~7 Days
  • HEK293T cell transient overexpression lysate (LY400555) as a positive control.
20 ug Included for FREE
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WB(1)
IHC(1)
 
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Gene NameHomo sapiens endothelial PAS domain protein 1 (EPAS1)
Synonyms:bHLHe73; ECYT4; HIF2A; HLF; MOP2; PASD2
ImmunogenHuman HIF-2 alpha amino acids 535-631.
BufferPBS and 0.1% sodium azide
Clone Nameep190b IsotypeIgG1
Species Reactivityhuman, rat Concentration1.6 mg/ml
Purification protein G purified
Guaranteed Application *WB, IHC Suggested DilutionsWB (1:500), IHC (1:150-1:300)
BackgroundHypoxia contributes significantly to the pathophysiology of major categories of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. HIF-2 alpha is predominantly expressed in highly vascularized tissues of adult humans and endothelial cells of the embryonic and adult mouse, whereas HIF-1 alpha functions primarily in extravascular tissues. HIF-2 alpha is also a potent activator of the tie-2 gene, which is known to be selectively expressed in endothelial cells.
Related Pathway
Adipogenesis

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WB Image
HIF-2 alpha detected in hypoxic human lysate. Lane 1: normoxic A549 lysate control, lane 2: hypoxic A549 lysate
IHC Image
Staining of heart, cardiac myocytes

 

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