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Home All anti-BIRC5 antibodies
Anti-BIRC5 Antibody
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for BIRC5 (NM_001168)
OriGene Data
| A synthetic peptide surrounding the phosphorylated serine 20 of the human Survivin protein. [Swiss-Prot #O15392] |
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| human |
1.25 mg/ml |
| WB |
WB:3 ug/ml |
| PBS, 30% Glycerol and 0.1% sodium azide |
| peptide affinity purified (Protein A or G Sepharose) |
Reference Data
| Homo sapiens baculoviral IAP repeat containing 5 (BIRC5), transcript variant 1 |
| API4; EPR-1 |
| NP_001159 |
| Survivin is a structurally unique inhibitor of apoptosis (IAP) that has been linked to protection from apoptosis, control of cell division, and cellular adaptation to stress. In order for survivin to provide this cytoprotection an interaction with at least one other IAP, such as XIAP, is necessary. It has recently been shown that Survivin is phosphorylated at Ser20 by protein kinase A (PKA) in the cytosol but not in the mitochondria. This phosphorylation on Ser20 disrupts the binding of cytosolic survivin to XIAP and therefore diminishes survivin's cytoprotective properties. |
Apoptosis Cell cycle |
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Detection of Survivin [Ser20] in phosphorylated recombinant protein (+), but not in unphosphorylated protein (-)
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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