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Home Antibody All anti-APBB1 antibodies

Anti-APBB1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA301423 Rabbit Polyclonal Antibody against Fe65 100ul $325 3-7 Days
LC400467 APBB1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(2)
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Also for APBB1 (NM_001164)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenRecombinant rat protein expressed in bacteria.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1: 1000
BufferPBS, 15% glycerol and 0.02% sodium azide
Purification Affinity purified

Reference Data

Target NameHomo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1), transcript variant 1
Alternative NameFE65; MGC:9072; RIR
Database LinkNP_001155
Entrez Gene 322 Human
Entrez Gene 11785 Mouse
Entrez Gene 29722 Rat
FunctionFE65 is a signaling adaptor of APP protein. The FE65/APP complex was shown to translocate into the cell nucleus and regulate gene expression. Genetic studies in mice validated FE65-APP interaction and molecular studies provided evidence on the role of the complex in abnormal signaling detected in brains of Alzheimer Disease patients.
Related PathwayTranscription Factors Alzheimer's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Detection of FE65 protein in HEK 293 cell lysate
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Western Blot: FE65 Antibody - Cells were transfected with the pCMV6-ENTRY control or pCMV6-ENTRY APBB1 cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APBB1.
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