Home Antibody All anti-ADFP antibodies
Also for ADFP (NM_001122)
|A synthetic peptide made to an internal portion of the human protein, within residues 150-250. [Swiss-Prot# Q99541]|
|human, monkey, porcine, mouse, bovine
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1: 1000
|PBS + 30% glycerol|
|peptide affinity purified (Protein A or G Sepharose)
|Homo sapiens perilipin 2 (PLIN2), transcript variant 1|
|Milk lipid globules from humans, cows and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material. This protein, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex that contains butyrophilin and xanthine oxidase. ADFP (Adipophilin) is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells. In tissues, however, expression of adipophilin is restricted to specific cell types, such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty change hepatocytes in alcoholic liver cirrhosis. ADFP may be a possible new marker for the identification of specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells. |
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Detection of human ADFP in human liver lysate
Immunohistochemistry-Paraffin: ADFP antibody was tested in mouse liver using DAB with hematoxylin counterstain.