Home Antibody All anti-PON1 antibodies
Also for PON1 (NM_000446)
|A synthetic peptide within the N-terminal region of the human protein (between residues 1-100). Swiss-Prot# P27169]|
||WB: 2 ug/ml
|Tris-glycine, 150mM NaCl and 0.05% sodium azide|
|Immunogen affinity purified
|Homo sapiens paraoxonase 1 (PON1)|
|ESA; MVCD5; PON|
|In humans, the paraoxonase (PON) gene family in humans has three members; PON1, PON2, and PON3. PON1 is synthesized primarily in the liver, and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). PON1 hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson's disease.|
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Detection of PON1 in HeLa whole cell extract using anti-PON1 at 2ug/ml.