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Anti-C1QC Antibody EPR2983


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal Antibody against C1QC (Clone EPR2983)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403541) , 20ug Explanation
100ul $325 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human C1q (subunit C) was used as an immunogen.
Clone NameEPR2983 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1: 1000~5000; IHC: 1: 100~250; ICC: 1: 100; FC: 1:50; IP: 1:50
Predicted MW Explanation 26 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens complement component 1, q subcomponent, C chain (C1QC), transcript variant 2
Alternative NameC1Q-C; C1QG
Database LinkNP_758957
Entrez Gene 714 Human
FunctionThe complement component C1 is a protein complex that consists of six subunits of C1q. Each C1q subunit of the complex is known to bind to immune complexes, which often are deposited in basement membrane. C1q consists of three different species of chains called A, B and C. It is a versatile recognition protein that triggers activation of the classical pathway of complement, where the first step involves the binding of the globular domain of Clq to the Fc regions of aggregated IgG or IgM. The C1q globular domain is a heterotrimer of the C-terminal halves of one A, one B, and one C chain, held together mainly by non-polar interactions, with a Ca2+ ion bound at the top. A modular organization has been suggested of the globular domain, consistent with the view that A, B, and C chains are functionally autonomous modules and have distinct and differential ligand-binding properties (1-3).
Related PathwaySecreted Protein Complement and coagulation cascadesPrion diseasesSystemic lupus erythematosus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - C1QG antibody [EPR2983]; All lanes : Anti-C1QG antibody [EPR2983] at 1/5000 dilution.Lane 1 : human plasma lysate.Lane 2 : human spleen lysate.Lane 3 : fetal marrow lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 26 kDa.Observed band size : 26 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - C1QG antibody [EPR2983]; Immunohistochemical analysis of paraffin-embedded human spleen tissue using 1/100-1/250 TA301374.


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