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Home Antibody All anti-ADIPOQ antibodies

Anti-ADIPOQ Antibody EPR3217

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301359
  • Rabbit Monoclonal Antibody against ADIPOQ (Clone EPR3217)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401510) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for ADIPOQ (NM_004797)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on human Adiponectin was used as an immunogen.
Clone NameEPR3217 IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:2,000~5,000; ICC: 1: 100~250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens adiponectin, C1Q and collagen domain containing (ADIPOQ), transcript variant 2
Alternative NameACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28
Database LinkNP_004788
FunctionAdiponectin is a multimeric adipocyte-specific secretory protein that regulates energy homeostasis, lipid metabolism, and insulin sensitivity with direct anti-diabetic, anti-atherogenic and anti-inflammatory properties. Adiponectin predominantly inhibits proliferation of myelomonocytic lineage cells and is an important negative regulator in hematopoiesis and immune systems (1, 2). Adiponectin is reported to possibly function as an endogenous factor involved in lipid catabolism and storage or whole body metabolism (3). It is decreased in obesity and has been demonstrated to inhibit tumor necrosis factor-alpha (TNF-alpha)-induced expression of endothelial adhesion molecules. Adiponectin modulates the inflammatory response of endothelial cells, possibly through cross talk between cAMP-PKA and NF-kappaB signaling pathways (4).
Related Pathway
Adipogenesis

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WB Image
Western blot - Adiponectin antibody [EPR3217]; All lanes : Anti-Adiponectin antibody [EPR3217] at 1/5000 dilution.Lane 1 : Fetal fat lysate.Lane 2 : Human plasma lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 26 kDa.Observed band size : 30 kDa .Additional bands at : 56 kDa (possible dimer).

 

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