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Home Antibody All anti-ALDOB antibodies

Anti-ALDOB Antibody EPR3138Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301312
  • Rabbit Monoclonal Antibody against ALDOB (Clone EPR3138Y)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400007) , 20ug
100ul $325 In Stock
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WB(1)
IHC(5)
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Also for ALDOB (NM_000035)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Aldolase B was used as an immunogen.
Clone NameEPR3138Y IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500~1000; IHC: 1: 100~250; FC: 1:20
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens aldolase B, fructose-bisphosphate (ALDOB)
Alternative NameALDB; ALDO2
Database LinkNP_000026
FunctionAldolase B is one of three known aldolase isoenzymes, and is found in kidney and small adult intestine where it is associated with aldolases A or C. Aldolase B catalyzes the reversible cleavage of fructose 1-phosphate into dihydroxyacetone phosphate and glyceraldehyde. It is involved in both glycolytic and gluconeogenic pathways, where its quaternary structure is critical for maintaining its full catalytic function. Hereditary fructose intolerance (HFI), a potentially fatal human autosomal recessive disease of carbohydrate metabolism, results with Aldolase B deficiency. Partially active Aldolase B, however, has been reported in an HFI individuals, which supports the hypothesis that adequate gluconeogenesis/glycolysis is maintained in HFI patients by the presence of partially active enzymes (1-4).
Related Pathway

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WB Image
Western blot - ALDOB antibody [EPR3138Y]; Anti-ALDOB antibody [EPR3138Y] at 1/1000 dilution + fetal kidney lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 39 kDa.Observed band size : 39 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ALDOB antibody [EPR3138Y]; TA301312, at 1/100 dilution, staining ALDOB in paraffin-embedded human liver tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-ALDOB antibody [EPR3138Y](TA301312); TA301312 showing positive staining in Normal kidney tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-ALDOB antibody [EPR3138Y](TA301312); TA301312 showing negative staining in Normal colon tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-ALDOB antibody [EPR3138Y](TA301312); TA301312 showing negative staining in Normal lung tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-ALDOB antibody [EPR3138Y](TA301312); TA301312 showing negative staining in Normal tonsil tissue.

 

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