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Anti-GC Antibody EP2923Y
|A synthetic peptide corresponding to residues within human VDBP was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:5000 - 1:20000; IHC-P: 1:100 - 1:250; ICC/IF: 1:100 - 1:250; FC: 1:40
|Does not react with Mouse, Rat. Is unsuitable for IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for IP.
|Homo sapiens group-specific component (vitamin D binding protein) (GC), transcript variant 1|
|DBP; DBP/GC; GRD3; VDBG; VDBP|
|Vitamin-D binding protein (VDBP, DBP, Gc) is a multifunctional plasma protein that has many physiologically important functions, ranging from transporting vitamin D3 metabolites, binding and sequestering globular actin and binding fatty acids to functioning in the immune system. It is a member of a multigene family including alpha-fetoprotein and albumin. It is a serum glycoprotein that reversibly binds and transports vitamin D and its metabolites to target cells. VDBP has a triple domain modular structure with extensive disulfide bonding that is characteristic of this protein family. VDBP receptors are constitutively expressed by malignant B-cells and in a transitory form by normal B-lymphocytes undergoing mitogen-induced activation (1-4). |
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Western blot - Vitamin D Binding Protein antibody [EP2923Y]; Anti-Vitamin D Binding protein antibody [EP2923Y] at 1/20000 dilution + human plasma at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 53 kDa.Observed band size : 53 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Vitamin D Binding Protein antibody [EP2923Y]; Immunohistochemical analysis of paraffin-embedded human liver using ab81307 at a 1/100 dilution.