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Home Antibody All anti-PEBP1 antibodies

Anti-PEBP1 Antibody EPR2875Y

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA301294 Rabbit Monoclonal Antibody against PEBP1 (Clone EPR2875Y) 100ul $325 In Stock
LC400913 PEBP1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(2)
IHC(1)
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Also for PEBP1 (NM_002567)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human RKIP was used as an immunogen.
Clone NameEPR2875Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:100; IHC-P: 1:250 - 1:500; IHC-Fr: Use at an assay dependent concentration; WB: 1:1000 - 1:5000; IP: 1:10; ICC/IF: Use at an assay dependent concentration
Predicted MW Explanation 21 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens phosphatidylethanolamine binding protein 1 (PEBP1)
Alternative NameHCNP; HCNPpp; HEL-210; HEL-S-34; PBP; PEBP; PEBP-1; RKIP
Database LinkNP_002558
Entrez Gene 5037 Human
Entrez Gene 23980 Mouse
Entrez Gene 29542 Rat
FunctionRaf kinase inhibitory protein (RKIP) belongs to the phosphatidylethanolamine-binding protein (PEBP) family. It is an inhibitor of the Raf/MEK/MAP kinase signaling cascade and is a suppressor of cancer metastasis (1). RKIP is involved in neural development, cardiac function and spermatogenesis and appears to have serine protease activity. The inhibition Raf-1-mediated phosphorylation of MEK results from RKIP binding to Raf-1. Dysregulated RKIP expression has the potential to contribute to pathophysiological processes including Alzheimer's disease and diabetic nephropathy (2). RKIP represents a novel effector of signal transduction pathways leading to apoptosis and a prognostic marker of the pathogenesis of human cancer cells and tumors (3).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - PBP antibody [EPR2875Y]; All lanes : Anti-PBP antibody [EPR2875Y] at 1/5000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : A549 cell lysate.Lane 3 : HepG2 cell lysate.Lane 4 : A431 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 21 kDa.Observed band size : 21 kDa.
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Western blot - Anti-PBP antibody [EPR2875Y]; Anti-PBP antibody [EPR2875Y] at 1/5000 dilution + Human PBP full length protein at 0.1 ug.Secondary.Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/5000 dilution.developed using the ECL technique.Performed under reducing conditions.Exposure time : 30 seconds
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PBP antibody [EPR2875Y]; Staining of formalin-fixed, paraffin-embedded human brain tissue using 1/250 TA301294.
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