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Anti-CAMK1 Antibody EPR2217Y
Also for CAMK1 (NM_003656)
|A specific peptide corresponding to residues on the N-terminus of human CaMKI was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:5000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens calcium/calmodulin-dependent protein kinase I (CAMK1)|
|Ca(+2)/calmodulin-dependent protein kinases (CaMKs) are activated upon binding of Ca(+2)/calmodulin. To gain maximal activity, CaMK I and CaMK IV can be further phosphorylated by an upstream kinase, CaMK kinase (CaMKK) (1). CaMKI is a Ca2+/calmodulin-dependent protein kinase that is widely expressed in eukaryotic cells and tissues but for which few, if any, physiological substrates are known (2). CaMKI has been shown to comprise a family of four structurally related isoforms (alpha, beta, gamma, and delta) encoded by separate genes with abundant expression in mature brain. In mouse brain, the four isoforms of CaMKI were found to exhibit distinct spatiotemporal expression during neuronal development. CaMKI may also have possible functional involvement of in the basal dendritic growth of hippocampal neurons (3) |
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Western blot - CaMKI antibody [EPR2217Y]; All lanes : Anti-CaMKI antibody [EPR2217Y] at 1/5000 dilution.Lane 1 : SH-SY5Y lysate.Lane 2 : human brain tissue lysate.Lane 3 : mouse brain tissue lysate.Lane 4 : rat brain tissue lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 41 kDa.Observed band size : 41 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody [EPR2217Y]; ab68234 at 1/100-1/250 dilution staining CaMKI in human kidney tissue sections.