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Home Antibody All anti-CAMK1 antibodies

Anti-CAMK1 Antibody EPR2217Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301185
  • Rabbit Monoclonal Antibody against CAMK1 (Clone EPR2217Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401210) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for CAMK1 (NM_003656)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA specific peptide corresponding to residues on the N-terminus of human CaMKI was used as an immunogen.
Clone NameEPR2217Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:5000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens calcium/calmodulin-dependent protein kinase I (CAMK1)
Alternative NameCAMKI
Database LinkNP_003647
Entrez Gene 8536 Human
Entrez Gene 52163 Mouse
Entrez Gene 171503 Rat
FunctionCa(+2)/calmodulin-dependent protein kinases (CaMKs) are activated upon binding of Ca(+2)/calmodulin. To gain maximal activity, CaMK I and CaMK IV can be further phosphorylated by an upstream kinase, CaMK kinase (CaMKK) (1). CaMKI is a Ca2+/calmodulin-dependent protein kinase that is widely expressed in eukaryotic cells and tissues but for which few, if any, physiological substrates are known (2). CaMKI has been shown to comprise a family of four structurally related isoforms (alpha, beta, gamma, and delta) encoded by separate genes with abundant expression in mature brain. In mouse brain, the four isoforms of CaMKI were found to exhibit distinct spatiotemporal expression during neuronal development. CaMKI may also have possible functional involvement of in the basal dendritic growth of hippocampal neurons (3)
Related PathwayProtein KinaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - CaMKI antibody [EPR2217Y]; All lanes : Anti-CaMKI antibody [EPR2217Y] at 1/5000 dilution.Lane 1 : SH-SY5Y lysate.Lane 2 : human brain tissue lysate.Lane 3 : mouse brain tissue lysate.Lane 4 : rat brain tissue lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 41 kDa.Observed band size : 41 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody [EPR2217Y]; TA301185 at 1/100-1/250 dilution staining CaMKI in human kidney tissue sections.

 

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