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Anti-CAMK1 Antibody EPR2217Y
Also for CAMK1 (NM_003656)
|A specific peptide corresponding to residues on the N-terminus of human CaMKI was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:5000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens calcium/calmodulin-dependent protein kinase I (CAMK1)|
Entrez Gene 8536 Human
Entrez Gene 52163 Mouse
Entrez Gene 171503 Rat
|Ca(+2)/calmodulin-dependent protein kinases (CaMKs) are activated upon binding of Ca(+2)/calmodulin. To gain maximal activity, CaMK I and CaMK IV can be further phosphorylated by an upstream kinase, CaMK kinase (CaMKK) (1). CaMKI is a Ca2+/calmodulin-dependent protein kinase that is widely expressed in eukaryotic cells and tissues but for which few, if any, physiological substrates are known (2). CaMKI has been shown to comprise a family of four structurally related isoforms (alpha, beta, gamma, and delta) encoded by separate genes with abundant expression in mature brain. In mouse brain, the four isoforms of CaMKI were found to exhibit distinct spatiotemporal expression during neuronal development. CaMKI may also have possible functional involvement of in the basal dendritic growth of hippocampal neurons (3) |
|Protein KinaseDruggable Genome |
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Western blot - CaMKI antibody [EPR2217Y]; All lanes : Anti-CaMKI antibody [EPR2217Y] at 1/5000 dilution.Lane 1 : SH-SY5Y lysate.Lane 2 : human brain tissue lysate.Lane 3 : mouse brain tissue lysate.Lane 4 : rat brain tissue lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 41 kDa.Observed band size : 41 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CaMKI antibody [EPR2217Y]; TA301185 at 1/100-1/250 dilution staining CaMKI in human kidney tissue sections.