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Anti-RAP1A Antibody EP879Y


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA301149 Rabbit Monoclonal Antibody against RAP1A (Clone EP879Y) 100ul $325 In Stock
LC419031 RAP1A HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for RAP1A (NM_002884)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human Rap 1 was used as an immunogen.
Clone NameEP879Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:500; IP: 1:40; ICC: 1:100 - 1:250
Predicted MW Explanation 21 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens RAP1A, member of RAS oncogene family (RAP1A), transcript variant 2
Alternative NameC21KG; G-22K; KREV-1; KREV1; RAP1; SMGP21
Database LinkNP_002875
Entrez Gene 5906 Human
Entrez Gene 109905 Mouse
Entrez Gene 295347 Rat
FunctionRap1, also known as Krev-1 and smg p21, is a member of the Ras super family of GTPases closely related to Ras. Two known isoforms of Rap1 exists, Rap1A and Rap1B which share 95% identity (1-2). As a molecular switch, Rap1 cycles between two conformational states depending on whether GDP bound (active form) or GTP bound (inactive form). Rap1 associates with a subset of Ras effectors including Raf-1, B-Raf, phosphoinositide 3-kinase, Ral GEFs, and PLC (3). Although its function is still unclear, Rap1 has been shown to be involved in the regulation of integrin-mediated cell adhesion (4).
Related PathwayDruggable Genome MAPK signaling pathwayChemokine signaling pathwayFocal adhesionLeukocyte transendothelial migrationLong-term potentiationNeurotrophin signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - RAP1 antibody [EP879Y]; Anti-RAP1A + RAP1B antibody [EP879Y] at 1/500 dilution + human brain lysate at 10 ug.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 21 kDa.Observed band size : 21 kDa.


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