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Anti-ITGB1 Antibody EPR1040Y

WB(1)

IHC(1)

Gene Name Homo sapiens integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (ITGB1), transcript variant 1A Synonyms: CD29; FNRB; GPIIA; MDF2; MSK12; VLA-BETA; VLAB Immunogen A synthetic peptide corresponding to the residues in human Integrin beta-1 (CD29) was used as immunogen. Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Clone Name EPR1040Y Isotype IgG Species Reactivity Human Concentration Purification (Protein A or G Sepharose) Guaranteed Application * WB, IHC Suggested Dilutions WB: 1:500; IHC: 1:250; ICC: 1:50~100 Background Integrin beta-1 (ITGB1, CD29, VLA-beta) is the beta subunit found in the integrin families, forming a heterodimer integrin receptor through non-covalent bonding with various integrin alpha subunits. Integrin heterodimer containing Integrin beta-1 binds to various cell surface and extracellular proteins (CD49a-f, CD51) to mediate cell to cell and cell to matrix adhesion (1). Integrin beta-1 plays a critical role in the cell adhesion and recognition in embryogenesis, hemostasis, immune response, tissue repair, metastatic diffusion of tumor cells and development (2, 3, 4). Related Pathway Focal Adhesion Hemostasis

Related Lysate from OriGene • Transient overexpression lysate of integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (ITGB1), transcript variant 1A Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • ITGB1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • ITGB1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Itgb1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • ITGB1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Itgb1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (ITGB1), transcript variant 1A as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (ITGB1), transcript variant 1A as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (ITGB1), transcript variant 1A as 200 ug transfection-ready DNA Related cDNA Clones • Homo sapiens integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (ITGB1), transcript variant 1A as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)