OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
Home Antibody All anti-CAV1 antibodies

Anti-CAV1 PHOSPHO Antibody EPR2288Y


Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
  • Rabbit Monoclonal Antibody against CAV1 (Clone EPR2288Y) (Phospho-specific)
100ul $325 3-7 Days
Add to Shopping Cart

OriGene Data

ImmunogenA phospho specifici peptide corresponding to residues surrounding tyrosine 14 of human caveolin-1 was used as an immunogen. This antibody detects caveolin-1 phosphorylated at tyrosine 14.
Clone NameEPR2288Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:2000 - 1:5000; ICC: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant 1
Alternative NameBSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21
Database LinkNP_001744
Entrez Gene 857 Human
FunctionCaveolins make up a family of proteins that are principal structural components of hairpin-like domains in the plasma membrane (1). It is believed that caveolins serve as scaffolding proteins for the integration of signal transduction. Three members of caveolins (caveolin-1, -2 and -3) have been identified, possessing different tissue distributions (2). Caveolins interact with multiple signaling molecules, such as the G-protein alpha subunit (1), tyrosine kinase receptors, PKCs, Src family tyrosine kinases and eNOS (2,3). Caveolin-1 has been implicated in the pathogenesis of mammary epithelial cell hyperplasia (4). Endothelial cell (EC) migration is a critical event during multiple physiological and pathological processes. The phosphorylatable Tyr14 residue of caveolin-1 is required for polarization of the protein during transmigration but does not alter polarization during planar movement.
Related PathwayTransmembraneDruggable Genome Focal adhesionViral myocarditis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Caveolin 1 (phospho Y14) antibody [EPR2288Y]; All lanes : Anti-Caveolin 1 (phospho Y14) [EPR2288Y] antibody at 1/2000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : HeLa cell lysate treated with pervanadate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/1000 dilution.Predicted band size : 20 kDa.Observed band size : 22 kDa .


Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title