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Home All anti-LCK antibodies
Anti-LCK Antibody EP2158Y
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
OriGene Data
| A synthetic phospho-peptide corresponding to residues surrounding Tyrosine 505 of human LCK was used as immunogen. |
| EP2158Y |
IgG |
| Human, Mouse |
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| WB |
WB: 1:: 1,000~10,000 |
| 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
| (Protein A or G Sepharose) |
Reference Data
| Homo sapiens lymphocyte-specific protein tyrosine kinase (LCK), transcript variant 2 |
| LSK; p56lck; pp58lck; YT16 |
| NP_005347 |
| The human T-cell or lymphocyte specific gene Lck/p56 is a member of the Src family of non-receptors tyrosine kinase. Mostly expressed in T cells, Lck has been shown to be critical for the normal development of T lymphocytes (1). Additionally, the N-terminal region of the tyrosine kinase Lck interacts with the cytoplasmic domains of CD4 and CD8 (2). Autophosphorylation at Tyr-394 appears to be required for maximum catalytic activity (3) but it can also be suppressed by phosphorylation of the carboxyl-terminal tyrosine Tyr-505 (4). |
Delta-Notch Signaling Pathway Hemostasis |
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* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Western blot analysis on Jurkat cell lysates using anti-Phospho-LCK (pY505), 1:10,000 dilution. Cells were either (A) untreated (B) treated with AP.
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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