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Home Antibody All anti-RPS6KA6 antibodies

Anti-RPS6KA6 Antibody EP1524Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301027
  • Rabbit Monoclonal Antibody against RPS6KA6 (Clone EP1524Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402340) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for RPS6KA6 (NM_014496)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues surrounding serine 235 of human Rsk 4 was used as an immunogen.
Clone NameEP1524Y IsotypeTissue culture supernatant
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:5000 - 1:10000; IHC-P: 1:50 - 1:100; ICC/IF: 1:100 - 1:250
BufferDoes not react with Rat. Is unsuitable for Flow Cyt or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 6 (RPS6KA6)
Alternative NamePP90RSK4; RSK4
Database LinkNP_055311
Entrez Gene 27330 Human
Entrez Gene 67071 Mouse
FunctionRSK4 is a member of the family of 90-kDa ribosomal S6 kinases (1). These proteins are a class of serine/threonine kinases that are activated in response to various extracellular signals, including growth factors, polypeptide hormones and neurotransmitters (2). RSK4 is most abundantly expressed in brain and kidney. The predicted protein of 746 amino acids shows a high level of homology to three previously isolated members of the human RSK family. RSK2 is involved in Coffin-Lowry syndrome and nonspecific MRX. The localization of RSK4 in the interval that is commonly deleted in mentally retarded males together with the high degree of amino acid identity with RSK2 suggests that RSK4 plays a role in normal neuronal development (3).
Related PathwayProtein KinaseDruggable Genome MAPK signaling pathwayOocyte meiosismTOR signaling pathwayLong-term potentiationNeurotrophin signaling pathwayProgesterone-mediated oocyte maturationMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - RSK4 (phospho S235) antibody [EP1524Y]; All lanes : Anti-RSK4 (phospho S235) antibody [EP1524Y] at 1/10000 dilution.Lane 1 : Hela cell lysate untreated.Lane 2 : Hela cell lysate treated with Calyculin A.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled anti-rabbit at 1/2000 dilution.Predicted band size : 84 kDa.Observed band size : 84 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - RSK4 (phospho S235) antibody [EP1524Y]; TA301027, at 1/50, staining human muscle tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

 

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