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Home Antibody All anti-RABAC1 antibodies

Anti-RABAC1 Antibody EPR1747Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301019
  • Rabbit Monoclonal Antibody against RABAC1 (Clone EPR1747Y)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401932) , 20ug
100ul 325 In Stock
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WB(1)
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Also for RABAC1 (NM_006423)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human PRA1 was used as an immunogen.
Clone NameEPR1747Y IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:20000; IP: 1:30; FC: 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC or IHC-P.

Reference Data

Target NameHomo sapiens Rab acceptor 1 (prenylated) (RABAC1)
Alternative NamePRA1; PRAF1; YIP3
Database LinkNP_006414
FunctionPRA1 (prenylated Rab acceptor) is a general regulator of Rab proteins. It has been shown that PRA1 interacts with Rab proteins and with VAMP2. Therefore PRA1 is probably an important factor for membrane traffic, linking together the function of Rab proteins and SNAREs (1). Human cells contain more than 60 small G proteins of the Rab family, which are localized to the surfaces of distinct membrane compartments and regulate transport vesicle formation, motility, docking and fusion. Prenylated Rabs also occur in the cytosol bound to GDI (guanine nucleotide dissociation inhibitor), which binds to Rabs in their inactive state (2).
Related Pathway

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WB Image
Western blot - PRA1 antibody [EPR1747Y] - Carboxyterminal end; Anti-PRA1 antibody [EPR1747Y] - Carboxyterminal end at 1/2000 dilution + 293 cell lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 21 kDa.Observed band size : 21 kDa.

 

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