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Anti-RPS6KA6 Antibody EP1982Y

WB(1)

IHC(1)

IF(1)

Gene Name Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 6 (RPS6KA6) Synonyms: PP90RSK4; RSK4 Immunogen A synthetic peptide corresponding to residues near the N-terminus of human Rsk 4 was used as an immunogen. Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Clone Name EP1982Y Isotype IgG Species Reactivity Human Concentration Purification (Protein A or G Sepharose) Guaranteed Application * WB, IHC, IF Suggested Dilutions WB: 1:250~500; IHC: 1:50~100; ICC: 1: 100~250; FC: 1:25 Background RSK4 is a member of the family of 90-kDa ribosomal S6 kinases (1). These proteins are a class of serine/threonine kinases that are activated in response to various extracellular signals, including growth factors, polypeptide hormones and neurotransmitters (2). RSK4 is most abundantly expressed in brain and kidney. The predicted protein of 746 amino acids shows a high level of homology to three previously isolated members of the human RSK family. RSK2 is involved in Coffin-Lowry syndrome and nonspecific MRX. The localization of RSK4 in the interval that is commonly deleted in mentally retarded males together with the high degree of amino acid identity with RSK2 suggests that RSK4 plays a role in normal neuronal development (3). Related Pathway MAPK signaling pathway

Related Lysate from OriGene • Transient overexpression lysate of ribosomal protein S6 kinase, 90kDa, polypeptide 6 (RPS6KA6) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • RPS6KA6 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • RPS6KA6 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Rps6ka6 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • RPS6KA6 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Rps6ka6 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 6 (RPS6KA6) as transfection-ready DNA • Lenti ORF clone of Human ribosomal protein S6 kinase, 90kDa, polypeptide 6 (RPS6KA6) , Myc-DDK-tagged • Lenti ORF clone of Human ribosomal protein S6 kinase, 90kDa, polypeptide 6 (RPS6KA6), mGFP tagged • GFP-tagged ORF clone of Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 6 (RPS6KA6) as transfection-ready DNA Related cDNA Clones • Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 6 (RPS6KA6) as transfection-ready DNA • Kinase deficient mutant (K105M) of Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 6 (RPS6KA6) as transfection-ready DNA • Kinase deficient mutant (K455M) of Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 6 (RPS6KA6) as transfection-ready DNA • Kinase deficient mutant (K455M) of Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 6 (RPS6KA6) as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)