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Anti-PRKD2 PHOSPHO Antibody EP1496Y


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal Antibody against PRKD2 (Clone EP1496Y) (Phospho-specific)
100ul $325 2 Weeks
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Also for PRKD2 (NM_016457)
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OriGene Data

ImmunogenA phosphor-synthetic peptide corresponding to residues surrounding Serine 876 was used as an immunogen. This antibody detects targets phosphorylated at Ser876.
Clone NameEP1496Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1: 1000; IP: 1:40
Predicted MW Explanation 97 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens protein kinase D2 (PRKD2), transcript variant 1
Alternative NameHSPC187; nPKC-D2; PKD2
Database LinkNP_057541
Entrez Gene 25865 Human
FunctionProtein kinases constitute a large superfamily of enzymes with key regulatory functions in nearly all signal transmission processes of eukaryotic cells; PKD2 is a novel phorbol ester- and growth factor-stimulated protein kinase (1). PKD2 is widely expressed in human and murine tissues and in cell lines such as HL60. In vivo, phorbol ester has been shown to autophosphorylate PKD2 in a synergistic fashion. Phosphorylation of Ser(876) of PKD2 correlated with the activation status of the kinase. The first zinc finger-like domain shares 88% identity to the corresponding domains in PKD/PKC-mu and PKC-nu (2).
Related PathwayProtein KinaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Protein Kinase D2 (phospho S876) antibody [EP1496Y]; All lanes : Anti-Protein Kinase D2 (phospho S876) antibody [EP1496Y] at 1/1000 dilution.Lane 1 : HeLa cell lysate, untreated.Lane 2 : HeLa cell lysate, treated with TPA.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP labeled at 1/2000 dilution.Predicted band size : 97 kDa.Observed band size : 105 kDa .


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