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Home Antibody All anti-IL10 antibodies

Anti-IL10 Antibody EP1115Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300793
  • Rabbit Monoclonal Antibody against IL10 (Clone EP1115Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424633) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
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Also for IL10 (NM_000572)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human IL-10 was used as an immunogen.
Clone NameEP1115Y IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:5000
Predicted MW Explanation 21 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC/IF.

Reference Data

Target NameHomo sapiens interleukin 10 (IL10)
Alternative NameCSIF; GVHDS; IL-10; IL10A; TGIF
Database LinkNP_000563
Entrez Gene 3586 Human
FunctionInterleukin (IL)-10 is a cytokine that inhibits production of other regulatory factors, including interferon gamma (IFN-gamma) and IL-2. A dimer of IL-10 is present in solution and is presumed to participate in receptor binding (1). IL-10 is a natural endogenous immunosuppressive cytokine that has been identified in human, murine, and other organisms. Human IL-10 (hIL-10) has high homology with murine IL-10 (mIL-10) as well as with an Epstein-Barr virus genome product BCRFI (2). IL-10 displays pleiotropic immunoregulatory properties. Human and murine IL-10 have a high amino acid sequence identity (ca. 73%) which includes the conservation of all four cysteine residues in human IL-10 and the first four out of five cysteine residues for murine IL-10. IL-10 is a highly alpha-helical protein containing two disulfide bonds, either one or both of which are critical for its structure and function (3).
Related PathwaySecreted ProteinES Cell Differentiation/IPSDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathwayT cell receptor signaling pathwayAsthmaAutoimmune thyroid diseaseSystemic lupus erythematosusMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - IL10 antibody [EP1115Y]; Anti-IL10 antibody [EP1115Y] at 1/5000 dilution + Recombinant protein (5ng).Secondary.Goat anti-Rabbit HRP labeled at 1/2000 dilution.Predicted band size : 21 kDa.Observed band size : 21 kDa.

 

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