OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-KRT19 antibodies

Anti-KRT19 Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300791
  • Rabbit Polyclonal Antibody against KRT19
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419428) , 20ug
100ul 379 3-7 Days
Add to Shopping Cart
WB(1)
IHC(1)
IF(1)
spacer
Also for KRT19 (NM_002276)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human CK-19 was used as an immunogen.
Clone Name IsotypeProtein A purified
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:20000; IP: 1:50; IHC-P: Use at an assay dependent dilution; ICC/IF: 1:250 - 1:500
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens keratin 19 (KRT19)
Alternative NameCK19; K19; K1CS
Database LinkNP_002267
FunctionKeratin polypeptide 19 (CK19) is a type I intermediate filament protein that is expressed in stratified and simple-type epithelia (1). Cytokeratins 8 and 19 concentrate at costameres of striated muscle and copurify with the dystrophin-glycoprotein complex, perhaps through the interaction of the cytokeratins with the actin-binding domain of dystrophin. Studies in COS-7 cells and in vitro showed that dystrophin binds directly and specifically to K19. Results show that dystrophin interacts through its ABD with CK19 specifically and are consistent with the idea that cytokeratins associate with dystrophin at the sarcolemma of striated muscle (2). CK19 is synthesized mainly in embryonic and adult simple epithelia, but has also been found in stratified epithelia as well. CK19 is the smallest known keratin and is remarkable in that, contrary to all other keratins, it does not have a designated partner for the formation of filaments, implying that regulation of its expression is different from other keratin-encoding genes (3).
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Cytokeratin 19 antibody; Anti-Cytokeratin 19 antibody at 1/20000 dilution + T47D cell lysate at 10 µg.Secondary.Goat anti-Rabbit HRP labeled. at 1/2000 dilution.Predicted band size : 44 kDa.Observed band size : 40 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - Cytokeratin 19 antibody; TA300791 (1:250) staining human Cytokeratin 19 in human bladder carcinoma tissue by immunohistochemistry using paraffin embedded tissue.
IF Image
Immunocytochemistry/ Immunofluorescence - Cytokeratin 19 antibody; Immunofluorescent staining of HeLa cells using TA300791 (1:250).

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title