Home Antibody All anti-KRT19 antibodies
Also for KRT19 (NM_002276)
|A synthetic peptide corresponding to residues near the N-terminus of human CK-19 was used as an immunogen.|
||Protein A purified
||0.5~1.0 mg/ml (Lot Dependent)
|WB, IHC, IF
||WB: 1:20000; IP: 1:50; IHC-P: Use at an assay dependent dilution; ICC/IF: 1:250 - 1:500
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt.
|Homo sapiens keratin 19 (KRT19)|
|CK19; K19; K1CS|
|Keratin polypeptide 19 (CK19) is a type I intermediate filament protein that is expressed in stratified and simple-type epithelia (1). Cytokeratins 8 and 19 concentrate at costameres of striated muscle and copurify with the dystrophin-glycoprotein complex, perhaps through the interaction of the cytokeratins with the actin-binding domain of dystrophin. Studies in COS-7 cells and in vitro showed that dystrophin binds directly and specifically to K19. Results show that dystrophin interacts through its ABD with CK19 specifically and are consistent with the idea that cytokeratins associate with dystrophin at the sarcolemma of striated muscle (2). CK19 is synthesized mainly in embryonic and adult simple epithelia, but has also been found in stratified epithelia as well. CK19 is the smallest known keratin and is remarkable in that, contrary to all other keratins, it does not have a designated partner for the formation of filaments, implying that regulation of its expression is different from other keratin-encoding genes (3). |
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Western blot - Cytokeratin 19 antibody; Anti-Cytokeratin 19 antibody at 1/20000 dilution + T47D cell lysate at 10 µg.Secondary.Goat anti-Rabbit HRP labeled. at 1/2000 dilution.Predicted band size : 44 kDa.Observed band size : 40 kDa .
Immunohistochemistry (Paraffin-embedded sections) - Cytokeratin 19 antibody; ab52907 (1:250) staining human Cytokeratin 19 in human bladder carcinoma tissue by immunohistochemistry using paraffin embedded tissue.
Immunocytochemistry/ Immunofluorescence - Cytokeratin 19 antibody; Immunofluorescent staining of HeLa cells using ab52907 (1:250).