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Home All anti-APOE antibodies

Anti-APOE Antibody

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA300742
  • Rabbit Polyclonal Antibody against APOE
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424959) , 20ug
100µl $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
30ul
$100
$50*
In Stock
Add to Shopping Cart
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)
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Also for APOE (NM_000041)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-term of human apolipoprotein E was used as an immunogen
Clone Name IsotypeIgG
Species ReactivityHuman Concentration
Guaranteed Application *WB Suggested DilutionsWB: 1:20,000; IHC: 1: 100 250; FC: 1:25; IP: 1: 100
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Reference Data

Target NameHomo sapiens apolipoprotein E (APOE)
Alternative NameAD2; LDLCQ5; LPG
Database LinkNP_000032
FunctionThe apolipoproteins are family of amphipathic lipoproteins that plays a crucial role in lipid metabolism. In particular, apolipoprotein E (apo E) is a major component of high density lipoproteins (HDL) chylomicrons and very low-density lipoprotein (VLDL), which functions to remove excess cholesterol. Apo E mediates lipid metabolism and cholesterol homeostasis by binding to several hepatic lipoprotein receptors, such as low density lipoprotein receptor (LDLR) and the LDLR-related protein (1). Apo E deficiency is linked to hyperlipoproteinemia type III; a genetic disorder characterized by elevated plasma cholesterol and triglyceride levels and accelerated coronary artery disease (2). Three major isoforms of Apo E (E2, E3, E4) has been identified, with E3 being the most common in human. E4 presence has been associated to increase probability of developing late-onset form of Alzheimer disease (3).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis using anti-Apo E, dilution 1:20,000.

 

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