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Home Antibody All anti-TUBB antibodies

Anti-TUBB Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300713
  • Rabbit Polyclonal Antibody against TUBB
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403597) , 20ug Explanation
100ul 379 In Stock
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WB(1)
IHC(1)
IF(1)
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Also for TUBB (NM_178014)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-term of human B-Tubulin was used as immunogen.
Clone Name IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsIHC-P: 1:100 - 1:250; WB: 1:1000 - 1:2000; IP: 1:50; ICC/IF: 1:50 - 1:100
Predicted MW Explanation 49 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Protein A purified
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens tubulin, beta class I (TUBB), transcript variant 2
Alternative NameCDCBM6; M40; OK/SW-cl.56; TUBB1; TUBB5
Database LinkNP_821133
Entrez Gene 203068 Human
FunctionMicrotubules are essential parts in eukaryotic cell structures, transportation, and mitosis and consists mainly of 2 soluble protein subunits, alpha and beta tubulin. Beta-tubulin binds to alpha tubulin to form tubulin heterodimer which is post-translationally modified (1). The tubulin dimer complex binds to GTP and assembles onto the positive ends of microtubules. After incorporation into the microtubules, bound GTP is hydrolyzed by beta tubulin. The stability of the dimer in the microtubules is depended on presence of beta tubulin, where dimer with GTP bound beta-tubulin is stable to microtubule incorporation (2). Mutation on beta-tubulin has been linked to anti-cancer drug resistance in lung cancers (3).
Related PathwayDruggable Genome Gap junctionPathogenic Escherichia coli infection

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-beta Tubulin antibody; Anti-beta Tubulin antibody at 1/1000 dilution + HeLa cell lysate at 10 ug.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 49 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-beta Tubulin antibody; Immunohistochemical analysis of paraffin-embedded Human muscle tissue labelling beta Tubulin with TA300713 at 1/100 dilution.
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-beta Tubulin antibody; Immunofluorescent analysis of HeLa cells labelling beta Tubulin with TA300713 at 1/50 dilution.

 

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