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Home Antibody All anti-EEF2K antibodies

Anti-EEF2K Antibody EP881Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300672
  • Rabbit Monoclonal Antibody against EEF2K (Clone EP881Y)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402241) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for EEF2K (NM_013302)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the C-terminal of human eEF2 was used as an immunogen.
Clone NameEP881Y IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1: 1000; ICC: 1:50 100; IP: 1:50
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens eukaryotic elongation factor-2 kinase (EEF2K)
Alternative NameeEF-2K; HSU93850
Database LinkNP_037434
FunctionEukaryotic elongation factor-2 kinase (eEF-2k) previously known as Ca2+/calmodulin-dependent protein kinase III, is an abundant cytoplasmic protein highly specific for elongation factor-2 (eEf-2) (1). Phosphorylation of eEF-2 by eEF-2 kinase on specific threonine residues results in the inactivation of eEF-2 and in termination of mRNA translation (2). The activity of eEF2 kinase is not only dependent upon Ca2+ ions, calmodulin (CaM) and insulin, but is also regulated both negatively and positively via phosphorylation by different protein kinases (AMPK, S6K1, p90 RSK) (3-4). There is also evidence that eEF-2 phosphorylation is involved in the regulation of cell cycle progression, cellular differentiation, oogensis and malignant tumors (5-6).
Related Pathway

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WB Image
Western blot - EEF2K antibody [EP881Y]; Anti-EEF2K antibody [EP881Y] at 1/1000 dilution + HEK293 cell lysate.Predicted band size : 82 kDa.Observed band size : 95 kDa .

 

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