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Home All anti-GRM1 antibodies
Anti-GRM1 Antibody EP691Y
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for GRM1 (NM_001274)
OriGene Data
| A synthetic peptide corresponding to C-terminal residues of human Chk1 was used as an immunogen. |
| EP691Y |
IgG |
| Human |
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| WB, IHC |
WB: 1: 10,000; IHC: 1:250 500; ICC: 1: 100 250; FC: 1: 160 |
| 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
| (Protein A or G Sepharose) |
Reference Data
| Homo sapiens checkpoint kinase 1 (CHEK1), transcript variant 3 |
| CHK1 |
| NP_001265 |
| Chk1 is involved in cell cycle arrest when DNA damage has occurred, and it plays an important role in DNA damage checkpoint, embryonic development and tumor suppression (1). Chk1 is activated in response to replication blocks and genotoxic stress, via phosphorylation of serines 317 and 345 (2). Activated Chk1 can bind to, phosphorylate (at serine 216) and inactivate cdc25c (3,4). Phosphorylation of cdc25c prevents activation of the CDC2-cyclin B complex and prevents entry into M-phase (3, 4). |
Cell cycle |
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Western blot analysis on HeLa cell lysate using anti-Chk1, dilution 1:10,000
IHC Image
Immunohistochemical analysis of paraffin-embedded human breast carcinoma using anti-CHK1.
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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