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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-CCL4 antibodies

Anti-CCL4 Antibody EP521Y

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA300656
  • Rabbit Monoclonal Antibody against CCL4 (Clone EP521Y)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401043) , 20ug
 100µl $325 3-7 Days Add to Shopping Cart
WB(1)
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Also for CCL4 (NM_002984)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens chemokine (C-C motif) ligand 4 (CCL4)
Synonyms:ACT2; AT744.1; G-26; HC21; LAG-1; LAG1; MIP-1-beta; MIP1B; MIP1B1; SCYA2; SCYA4
ImmunogenA synthetic peptide corresponding to residues in the N-terminus of human MIP-1 beta/CCL4 was used as an immunogen.
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Clone NameEP521Y IsotypeIgG
Species ReactivityHuman Concentration
Guaranteed Application *WB Suggested DilutionsWB: 1:1000-10000
BackgroundMacrophage inflammatory protein-1 beta (MIP-1 beta/CCL4) belongs to the intercrine beta (chemokine CC) family (1). MIP-1 beta functions to promote accumulation of lymphocyte, marcorphages, monocytes, and NK cells during various inflammatory conditions through its chemotactic properties. MIP-1 beta is an essential inhibitor of cell infection by human immunodeficiency virus type 1 (HIV-1). MIP-1 beta inhibits HIV-1 by blocking or down-regulating the receptors CCR5, one of coreceptor for HIV-1 entry (2). In human, MIP-1 beta exhibits specific attractant activities to CD4+ T lymphocytes, with minor activities to T cells from naive (CD45RA) phenotype (3).
Related Pathway
Cytokine-cytokine receptor interaction
Toll-like receptor signaling pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot of anti-MIP1 beta (N-term), dilution 1:500,000 (approximately 0.05ug/lane [0.5ug/200ul] of recombinant protein was loaded on the membrane)

 

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