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Home Antibody All anti-CCL4 antibodies

Anti-CCL4 Antibody EP494Y

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SKU Description Amount Price Availability*  
TA300655
  • Rabbit Monoclonal Antibody against CCL4 (Clone EP494Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401043) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the C-terminus of human MIP-1 beta/CCL4 was used as an immunogen.
Clone NameEP494Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:500000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC or IHC.

Reference Data

Target NameHomo sapiens chemokine (C-C motif) ligand 4 (CCL4)
Alternative NameACT2; AT744.1; G-26; HC21; LAG-1; LAG1; MIP-1-beta; MIP1B; MIP1B1; SCYA2; SCYA4
Database LinkNP_002975
Entrez Gene 6351 Human
FunctionMacrophage inflammatory protein-1 beta (MIP-1 beta/CCL4) belongs to the intercrine beta (chemokine CC) family (1). MIP-1 beta functions to promote accumulation of lymphocyte, marcorphages, monocytes, and NK cells during various inflammatory conditions through its chemotactic properties. MIP-1 beta is an essential inhibitor of cell infection by human immunodeficiency virus type 1 (HIV-1). MIP-1 beta inhibits HIV-1 by blocking or down-regulating the receptors CCR5, one of coreceptor for HIV-1 entry (2). In human, MIP-1 beta exhibits specific attractant activities to CD4+ T lymphocytes, with minor activities to T cells from naive (CD45RA) phenotype (3).
Related PathwaySecreted ProteinTransmembraneDruggable Genome Cytokine-cytokine receptor interactionChemokine signaling pathwayToll-like receptor signaling pathwayCytosolic DNA-sensing pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Macrophage Inflammatory Protein 1 beta antibody [EP494Y]; Anti-Macrophage Inflammatory Protein 1 beta antibody [EP494Y] at 1/500000 dilution + recombinant protein at 0.05 ug.Predicted band size : 10 kDa.Observed band size : 10 kDa.
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