Home Antibody All anti-PAK4 antibodies
Also for PAK4 (NM_005884)
|A synthetic peptide corresponding to residues in the N-terminus of human PAK4 was used as immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
|Preservative: 0.01% Sodium azide|
Constituents: 50% Glycerol, 0.05% BSA
|Protein A purified
|Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
|Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 1|
|p21(CDKN1A)-activated kinase 4; p21-activated kinase 4; protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs; p21 protein (Cdc42/Rac)-activated kinase 4|
|p21-activated kinase 4 (PAK4) is a member of a family of serine/threonine protein kinase defined by their interaction with the small GTPases, Cdc42 and Rac (1-2). The PAK proteins can be essentially divided into two categories, groups I (PAK1, PAK2 and PAK3) and group II (PAK4, PAK5 and PAK6), based on their structures (3). PAK4 has been shown to regulate cytoskeletal organization and to protect cells from apoptosis induced by multiple stimuli, including serum withdrawal, tumor necrosis factor- (TNF) treatment, or UV irradiation (4). PAK4 expression is elevated in many cancer cell lines, and activated PAK4 is highly transforming, suggesting an important role in tumorigenesis (5). |
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Western blot - Anti-PAK4 antibody; Anti-PAK4 antibody at 1/1000 dilution + SH-SY-5Y cell lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 64 kDa.Observed band size : 68 kDa .