Search:     All Products Assays Human cDNA clone, untagged Human cDNA clone, tagged RNAi 3'-UTR Clone Human Primer Mouse cDNA clone, untagged Mouse cDNA clone, tagged Rat ORF clone, untagged Rat ORF clone, tagged Virus ORF clone, tagged Mouse Primer qPCR Standard Proteins Mass Spec Standard Antibodies Lysate MicroRNA Expression Plasmids MicroRNA primer pairs MicroRNA template standards Other Products

 

Antibody

UltraMAB IHC Antibodies

TrueMAB Primary Antibodies

Anti-tag Antibodies

ELISA Antibodies

Luminex Antibodies

Secondary Antibodies

Antibody Accessories

Antibody Service

 

Related Products

 

Useful Links

FAQs

Anti-HSPD1 Antibody

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IHC(1)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues in human Heat Shock Protein 60 was used as immunogen.
Clone Name		Isotype	IgG
Species Reactivity	Human, Mouse, Rat	Concentration
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1: 20,000-50,000; IHC: 1:250-500; ICC: 1:250-500; FC: 1:20; IP: 1:50
Buffer	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1
Alternative Name	CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13
Database Link	NP_002147
Function	The 60 kDa heat shock protein (HSP60) is a highly conserved protein that act as a chaperone involved in correct folding of newly synthesized proteins (1-2). Mainly expressed in mitochondria, HPS60 has also been found in the cytosol of normal heart and muscle cells. In normal cardiac myocytes, cytosolic HSP60 complexes with Bax, Bak and Bcl-XL (3). While over expression of HSP60 prevents apoptosis in cardiac cells; is has also been shown that HSP60 accelerated the activation of Caspase 3 during apoptosis (4-5). Therefore, the role of HSP60 in apoptosis may be both pro- and anti-apoptotic, depending on the cell type, or apoptotic stimulus.
Related Pathway

Related Lysate from OriGene • Transient overexpression lysate of heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • HSPD1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • HSPD1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Hspd1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • HSPD1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Hspd1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1 as transfection-ready DNA • Lenti ORF clone of Human heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1 , Myc-DDK-tagged • Lenti ORF clone of Human heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged • Myc-DDK-tagged ORF clone of Homo sapiens heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1 as 200 ug transfection-ready DNA Related cDNA Clones • Homo sapiens heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial protein, transcript variant 1 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)