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Home Antibody All anti-EEF2K antibodies

Anti-EEF2K Antibody EP724Y


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA300638 Rabbit Monoclonal Antibody against EEF2K (Clone EP724Y) 100ul $325 In Stock
LC402241 EEF2K HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for EEF2K (NM_013302)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the Calmodulin binding region of human eEF2 was used as immunogen.
Clone NameEP724Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:50000; IP: 1:20
Predicted MW Explanation 82 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target Nameeukaryotic elongation factor 2 kinase
Alternative NameHSU93850|eEF-2K
Database LinkNP_037434
Entrez Gene 29904 Human
Entrez Gene 13631 Mouse
Entrez Gene 25435 Rat
FunctionEukaryotic elongation factor-2 kinase (eEF-2k) previously known as Ca2+/calmodulin-dependent protein kinase III, is an abundant cytoplasmic protein highly specific for elongation factor-2 (eEf-2) (1). Phosphorylation of eEF-2 by eEF-2 kinase on specific threonine residues results in the inactivation of eEF-2 and in termination of mRNA translation (2). The activity of eEF2 kinase is not only dependent upon Ca2+ ions, calmodulin (CaM) and insulin, but is also regulated both negatively and positively by phosphorylation by different protein kinases (AMPK, S6K1, p90 RSK) (3-4). There is also evidence that eEF-2 phosphorylation is involved in the regulation of cell cycle progression, cellular differentiation, oogensis and malignant tumors (5-6).
Related PathwayProtein KinaseDruggable Genome

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WB Image
Western blot - EEF2K antibody [EP724Y]; All lanes : Anti-EEF2K antibody [EP724Y] at 1/50000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 82 kDa.Observed band size : 95 kDa .


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