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Anti-FLOT1 Antibody EP446Y
Also for FLOT1 (NM_005803)
|A synthetic peptide corresponding to residues in human Flotillin-1 was used as immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:500 - 1:1000
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Homo sapiens flotillin 1 (FLOT1)|
|OTTHUMP00000029208; integral membrane component of caveolae; flotillin 1|
|Flotillin-1, also known as Reggie-2, belongs to a larger family of proteins that share an evolutionarily conserved stomatin/prohibitin/flotillin/HflK/C (SPFH) domain (1). Flotillin-1 is a lipid raft-associated protein that has been implicated in various cellular processes. Flotillin was first found in cells that lack morphologically definable caveolae, as well as in non-caveolar membranes (2) and was subsequently identified in low density detergent-insoluble complexes of endothelial cells, where they were termed flotillins (3). As well as its postulated role in neuronal regeneration, flotilllin-1 has been implicated in insulin signaling to trigger glucose transporter redistribution in adipocytes (4) Flotillin also associates with phagosomes in macrophages (5). |
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Western blot - Flotillin 1 antibody [EP446Y]; Anti-Flotillin 1 antibody [EP446Y] at 1/500 dilution + K562 cell lysate .Predicted band size : 48 kDa.Observed band size : 48 kDa.