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Home Antibody All anti-SMAD1 antibodies

Anti-SMAD1 Antibody EP565Y

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SKU Description Amount Price Availability*  
TA300571
  • Rabbit Monoclonal Antibody against SMAD1 (Clone EP565Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416996) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IF(1)
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Also for SMAD1 (NM_005900)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Smad1 was used as immunogen.
Clone NameEP565Y IsotypeIgG
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:500-2,000; ICC: 1: 100-250
Predicted MW Explanation 52 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Does not react with Rat

Reference Data

Target NameHomo sapiens SMAD family member 1 (SMAD1), transcript variant 1
Alternative NameBSP-1; BSP1; JV4-1; JV41; MADH1; MADR1
Database LinkNP_005891
Entrez Gene 4086 Human
Entrez Gene 17125 Mouse
FunctionSmad 1 is a member of the Mothers Against Dpp (MAD)-related family of proteins. So far, eight Smads have been identified and can be divided in 3 subgroups based on their structure and function; pathway-restricted, common mediator and inhibitory. Smad 1, 5 and 8 serve as pathway-restricted Smads for the bone morphogenetic proteins (BMPs) signaling pathway (1). Smad 1 is involved in cell growth, apoptosis, morphogenesis, development and immune response (2). After phosphorylaion by the BMP type 1 receptor kinase Smad1 and co-Smad4 form a heteromeric complex and translocate to the nucleus to regulate transcription of target genes (3).
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayStem cell relevant signaling - TGFb/BMP signaling pathwayES Cell Differentiation/IPSCancer stem cellsTranscription FactorsDruggable Genome TGF-beta signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Smad1 antibody [EP435E]; Anti-Smad1 antibody [EP565Y] at 1/500 dilution + HeLa cell lysate.Predicted band size : 52 kDa.Observed band size : 58 kDa .
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Immunocytochemistry/ Immunofluorescence - Smad1 antibody [EP435E]; Ab33902, at 1/100 dilution, staining Smad1 in HeLa cells by Immunocytochemistry/Immunofluorescence.
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