OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-SMAD1 antibodies

Anti-SMAD1 Antibody EP565Y

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300571
  • Rabbit Monoclonal Antibody against SMAD1 (Clone EP565Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416996) , 20ug Explanation
100ul 325 3-7 Days
Add to Shopping Cart
spacer
WB(1)
IF(1)
spacer
Also for SMAD1 (NM_005900)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Smad1 was used as immunogen.
Clone NameEP565Y IsotypeIgG
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:500-2,000; ICC: 1: 100-250
Predicted MW Explanation 52 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Does not react with Rat

Reference Data

Target NameHomo sapiens SMAD family member 1 (SMAD1), transcript variant 1
Alternative NameBSP-1; BSP1; JV4-1; JV41; MADH1; MADR1
Database LinkNP_005891
Entrez Gene 4086 Human
Entrez Gene 17125 Mouse
FunctionSmad 1 is a member of the Mothers Against Dpp (MAD)-related family of proteins. So far, eight Smads have been identified and can be divided in 3 subgroups based on their structure and function; pathway-restricted, common mediator and inhibitory. Smad 1, 5 and 8 serve as pathway-restricted Smads for the bone morphogenetic proteins (BMPs) signaling pathway (1). Smad 1 is involved in cell growth, apoptosis, morphogenesis, development and immune response (2). After phosphorylaion by the BMP type 1 receptor kinase Smad1 and co-Smad4 form a heteromeric complex and translocate to the nucleus to regulate transcription of target genes (3).
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayStem cell relevant signaling - TGFb/BMP signaling pathwayES Cell Differentiation/IPSCancer stem cellsTranscription FactorsDruggable Genome TGF-beta signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Smad1 antibody [EP435E]; Anti-Smad1 antibody [EP565Y] at 1/500 dilution + HeLa cell lysate.Predicted band size : 52 kDa.Observed band size : 58 kDa .
IF Image
Immunocytochemistry/ Immunofluorescence - Smad1 antibody [EP435E]; Ab33902, at 1/100 dilution, staining Smad1 in HeLa cells by Immunocytochemistry/Immunofluorescence.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title