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Home Antibody All anti-TP53 antibodies

Anti-TP53 Antibody EP155Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300566
  • Rabbit Monoclonal Antibody against TP53 (Clone EP155Y)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400186) , 20ug
100ul $325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for TP53 (NM_000546)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the C-term of human Ubiquitin was used as immunogen. The antibody will detect p53 phosphorylation on Serine 392.
Clone NameEP155Y IsotypeIgG
Species ReactivityHuman, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000 - 1:5000; IHC-P: 1:100 - 1:250; ICC/IF: 1:250 - 1:500; IP: 1:80
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens tumor protein p53 (TP53), transcript variant 1
Alternative NameBCC7; LFS1; P53; TRP53
Database LinkNP_000537
Functionp53 acts as both a tumor-suppressor and transcription factor that, upon activation by DNA damage and other cellular stress signals, leads to the transcription of genes triggering cell-cycle arrest, apoptosis, and DNA repair (1,2). The gene for the nuclear phosphoprotein p53 is the most commonly mutated gene yet identified in human cancers (3). p53 is frequently mutated or inactivated in about 60% of cancers (4,5).
Related Pathway
Apoptosis
Cell cycle
Delta-Notch Signaling Pathway
MAPK signaling pathway
Senescence and Autophagy
TGF Beta Signaling Pathway
Wnt Signaling Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - p53 (phospho S392) antibody [EP155Y]; All lanes : Anti-p53 (phospho S392) antibody [EP155Y] at 1/500 dilution.Lane 1 : MCF7 cell lysate untreated.Lane 2 : MCF7 cell lysate treated with 5 ug/ml Actinomycin for 3hrs.Lane 3 : MCF7 cell lysate treated with 5 ug/ml Actinomycin for 6hrs.Lane 4 : MCF7 cell lysate treated with 5 ug/ml Actinomycin for 18hrs.Predicted band size : 44 kDa.Observed band size : 53 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - p53 (phospho S392) antibody [EP155Y]; Ab33889, at a 1/100 dilution, staining p53 in paraffin embedded human prostate adenocarcinoma tissue by Immunohistochemistry.
IF Image
Immunocytochemistry/ Immunofluorescence - p53 (phospho S392) antibody [EP155Y]; Ab33889, at a 1/250 dilution, staining p53 in A431 cells by Immunofluorescence.

 

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