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Home Antibody All anti-BMX antibodies

Anti-BMX Antibody Y396


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA300521 Rabbit Monoclonal Antibody against BMX (Clone Y396) 100ul $325 In Stock
LC400648 BMX HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the pleckstrin homology domain of human ETK/BMX was used as immunogen.
Clone NameY396 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:2000; IP: 1:50
Predicted MW Explanation 78 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or ICC.

Reference Data

Target NameHomo sapiens BMX non-receptor tyrosine kinase (BMX), transcript variant 2
Alternative NameETK; PSCTK2; PSCTK3
Database LinkNP_001712
Entrez Gene 660 Human
Entrez Gene 12169 Mouse
Entrez Gene 367786 Rat
FunctionEtk (epithelial and endothelial tyrosine kinase) is a member of the TEC family of non-receptor protein tyrosine kinase which includes Btk, Itk and TEC. Etk is composed of a pleckstrin domain, an SH3 and SH2 domain and a catalytic kinase domain (1). Etk is implicated in cell adhesion, migration, proliferation, survival as well as signal transduction (2). In PCA, Etk activation by IL-6 is mediated by PI3-K (3). It as also been shown in TNF-induced angiogenesis, TNF activates Etk through TNFR2 (4). Additionally, in the AR pathway, ETtk, FAK and Src form a complex. FAK activates Src which in turn activates Etk by phosphorylating Etk tyrosine residue 566 (5).
Related PathwayProtein KinaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - BMX antibody [Y396]; Anti-BMX antibody [Y396] at 1/500 dilution + HeLa cell lysate.Predicted band size : 78 kDa.Observed band size : 75 kDa .


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