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Home Antibody All anti-TP53 antibodies

Anti-TP53 Antibody Y43

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300484
  • Rabbit Monoclonal Antibody against TP53 (Clone Y43)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400186) , 20ug
100ul $325 3-7 Days
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WB(1)
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Also for TP53 (NM_000546)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic phospho-peptide corresponding to residues surrounding Serine 9 of human p53 was used as immunogen. The antibody will detectp53 phosphorylation on Serine 9. This antibody may also detect all splice isoforms 2 based on sequence homology.
Clone NameY43 IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1: 1,000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification IgG fraction
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens tumor protein p53 (TP53), transcript variant 1
Alternative NameBCC7; LFS1; P53; TRP53
Database LinkNP_000537
Functionp53 acts as both a tumor-suppressor and transcription factor that, upon activation by DNA damage and other cellular stress signals, leads to the transcription of genes triggering cell-cycle arrest, apoptosis, and DNA repair (1,2). The gene for the nuclear phosphoprotein p53 is the most commonly mutated gene yet identified in human cancers (3). p53 is frequently mutated or inactivated in about 60% of cancers (4,5).
Related Pathway
Apoptosis
Cell cycle
Delta-Notch Signaling Pathway
MAPK signaling pathway
Senescence and Autophagy
TGF Beta Signaling Pathway
Wnt Signaling Pathway

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WB Image
Western blot - p53 (phospho S9) antibody [Y43]; All lanes : Anti-p53 (phospho S9) antibody [Y43] at 1/1000 dilution.Lane 1 : Untreated A431 cell lysate.Lane 2 : A431 cell lysate treated with methyl methanesulfonate.Predicted band size : 44 kDa.Observed band size : 50 kDa .

 

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