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Anti-MAPK14 Antibody Y122
Also for MAPK14 (NM_001315)
|A synthetic peptide corresponding to residues near the C-terminus of human p38 MAP kinase was used as immunogen. Predicted to react with CSBP1 splice form based on sequence homology.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||ICC/IF: 1:100 - 1:250; WB: 1:1000 - 1:10000; IHC-P: Use at an assay dependent dilution
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens mitogen-activated protein kinase 14 (MAPK14), transcript variant 1|
|CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; p38; p38ALPHA; PRKM14; PRKM15; RK; SAPK2A|
|p38 MAP kinase is a mitogen-activated protein kinase that functions in various intracellular signaling cascades controlling cellular stress responses. p38 MAP kinase is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccharides (LPS), UV light and growth factors (1-3). MKK3 and SEK activate p38 MAP kinase by phosphorylation at adjacent threonine and tyrosine residues, Thr180 and Tyr182 (3,4). Activated p38 MAP kinase phosphorylates numerous downstream targets, including transcription factor ATF-2 (4). |
EGFR1 Signaling Pathway
MAPK signaling pathway
Senescence and Autophagy
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway
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Western blot - p38 antibody [Y122]; All lanes : Anti-p38 antibody [Y122] at 1/50000 dilution.Lane 1 : Hela cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : K562 cell lysate.Lane 4 : MCF7 cell lysate.Predicted band size : 41 kDa.Observed band size : 42 kDa .
Immunohistochemistry (Paraffin-embedded sections) - p38 antibody [Y122]; Ab32142, at a 1/100 dilution, staining p38 in paraffin embedded human skin carcinoma tissue by immunohistochemistry.
Immunofluorescence - p38 antibody [Y122]; Ab32142, at a 1/100 dilution, staining p38 in MCF7 cells by Immunofluorescence.