OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right

OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
View All Citations >>
 Home All anti-NBN antibodies

Anti-NBN Antibody Y112

div

Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA300448
  • Rabbit Monoclonal Antibody against NBN (Clone Y112)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419300) , 20ug
 100µl $325 3-7 Days Add to Shopping Cart
WB(1)
IHC(1)
IF(1)
Gene NameHomo sapiens nibrin (NBN)
Synonyms:AT-V1; AT-V2; ATV; NBS; NBS1; P95
ImmunogenA synthetic peptide corresponding to residues near C-terminus of human Nibrin was used as immunogen
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Clone NameY112 IsotypeIgG
Species ReactivityHuman, Mouse Concentration
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:500; IHC: 1:50; ICC: 1:50; IP: 1:60
BackgroundNibrin (also known as NBS1 or p95) contains 2 modules found in cell cycle check point; a forkhead-associated domain & a BRCA1 C-teminal repeat (1). In mammalian cells, Nibrin forms a complex with Mre11 & Rad50 (MRN). Nuclear localization of the MRN complex is relevant for chromosomal stability, meiotic recombination, DNA repair & telomere maintenance in eukaryotic cells(2-4). Mutation in Nibrin & Mre11 causes respectively two related disorders, Nijmegen breakage syndrome (NBS) & Ataxia-Telangiectasia- like disorder (ATLD).
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis on analysis on Hela cell lysate using anti-Nibrin/NBS1, dilution 1:500.
IHC Image
Immunohistochemical analysis of paraffin-embedded human skin carcinoma using anti-Nibrin/NBS1.
IF Image
Immunofluorescent staining of HeLa cells using anti-Nibrin/NBS1.

 

spacer
Inc 5000 Healthcare Company Copyright © 2013 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title