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Anti-STAT6 Antibody YE361

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IHC(1)

IF(1)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues near C-terminus of human Stat-6 was used as immunogen. The antibody does not cross-react with other Stat family members.
Clone Name	YE361	Isotype	IgG
Species Reactivity	Human, Mouse	Concentration
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB: 1:500; IHC: 1: 100-250; ICC: 1: 100; IP: 1:80
Buffer	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2
Alternative Name	D12S1644; IL-4-STAT; STAT6B; STAT6C
Database Link	NP_003144
Function	Janus family tyrosine kinases (Jaks) and signal transducers and activators of transcription (STATs) are involved in mediating gene expression in response to cytokines and interferons. Jaks associate with cytokine receptors; upon ligand binding, Jaks phosphorylate the receptor. The phosphorylated receptors are bound by SH2-containing proteins, one class of which is the STATs. Activated STATs, then, translocate to the nucleus to mediate gene transcription (1,2). Stat-6 is tyrosine phosphorylated in response to cellular interaction with IL-3 and IL-4 (3,4).
Related Pathway	Adipogenesis Jak-STAT signaling pathway

Related Lysate from OriGene • Transient overexpression lysate of signal transducer and activator of transcription 6, interleukin-4 induced (STAT6) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • STAT6 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • STAT6 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Stat6 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • STAT6 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Stat6 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2 as transfection-ready DNA • Lenti ORF clone of Human signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2, mGFP tagged • Lenti ORF clone of Human signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2 , Myc-DDK-tagged Related cDNA Clones • Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)